
D-penicillamine interferes with elastin and collagen metabolism and produces several cutaneous and multi-systemic side-effects. We present two cases of Wilson's disease who on long-term penicillamine therapy developed drug-induced degenerative dermopathy manifesting as skin fragility over pressure sites and cutis laxa-like changes.
penicillamine, Degenerative dermopathy, chronic therapy, RL1-803, Case Report, Dermatology
penicillamine, Degenerative dermopathy, chronic therapy, RL1-803, Case Report, Dermatology
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