publication . Article . 2016

Reactive oxygen species, health and longevity

Vittorio Emanuele Bianchi; Giancarlo Falcioni;
Open Access English
  • Published: 01 Sep 2016 Journal: AIMS Molecular Science, volume 3, issue 4, pages 479-504 (issn: 2372-0301, Copyright policy)
  • Publisher: AIMS Press
  • Country: Italy
Reactive oxygen species (ROS) are considered responsible of ageing in animal and humans. Mitochondria are both source and target of ROS. Various strategies to reduce ROS production have been considered to extend lifespan. Caloric restriction, exercise, and antioxidants are thought to be able to protect cells from structural and functional damage. However, there is evidence that ROS production has a detrimental effect on health, but at physiological levels are necessary to stimulate longevity. They play an important effect on secondary signal transduction stimulating innate immunology and mitochondriogenesis. During exercise at moderate intensity, skeletal muscle...
Persistent Identifiers
free text keywords: reactive oxygen species, antioxidants, aging, longevity, mitochondriogenesis, vitamin C, vitamin E, caloric restriction., lcsh:Science (General), lcsh:Q1-390, Mitochondrion, Internal medicine, medicine.medical_specialty, medicine, Ageing, Endocrinology, Signal transduction, Reactive oxygen species, chemistry.chemical_classification, chemistry, Muscle atrophy, medicine.symptom, Longevity, media_common.quotation_subject, media_common, Antioxidant, medicine.medical_treatment, Gerontology, Biology, Muscle adaptation
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