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Mathematical Biosciences and Engineering
Article . 2024 . Peer-reviewed
Data sources: Crossref
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https://dx.doi.org/10.48550/ar...
Article . 2024
License: CC BY
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Mathematical and numerical analysis for PDE systems modeling intravascular drug release from arterial stents and transport in arterial tissue

Authors: Xiaobing Feng; Tingao Jiang;

Mathematical and numerical analysis for PDE systems modeling intravascular drug release from arterial stents and transport in arterial tissue

Abstract

<abstract><p>This paper is concerned with the PDE (partial differential equation) and numerical analysis of a modified one-dimensional intravascular stent model. It is proved that the modified model has a unique weak solution by using the Galerkin method combined with a compactness argument. A semi-discrete finite-element method and a fully discrete scheme using the Euler time-stepping have been formulated for the PDE model. Optimal order error estimates in the energy norm are proved for both schemes. Numerical results are presented, along with comparisons between different decoupling strategies and time-stepping schemes. Lastly, extensions of the model and its PDE and numerical analysis results to the two-dimensional case are also briefly discussed.</p></abstract>

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Keywords

Finite Element Analysis, intravascular stent, Mathematics - Analysis of PDEs, well-posedness, QA1-939, FOS: Mathematics, Humans, Computer Simulation, Mathematics - Numerical Analysis, drug release, Models, Cardiovascular, Drug-Eluting Stents, galerkin finite-element method, Arteries, Numerical Analysis (math.NA), diffusion-advection-reaction equation, error estimates, Stents, 35K57, 35Q92, 65M22, 65M60, 92B05, pharmacokinetics, TP248.13-248.65, Mathematics, Algorithms, Biotechnology, Analysis of PDEs (math.AP)

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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