To stay sustain in the highly challenging and competitive global market is essential for all businesses. To get highest productivity in companies, interpersonal communication fills the gap between various system and management. Motivated employees for better performance, efficient communication is must to achieve this. This study examines the association between three communication patterns i.e. Upward Communication, Downward Communication, Horizontal Communication & Job satisfaction of employees work in large scale industries in Pune. From this study researchers have tried to indicate a positive relationship between interpersonal communication and performance of employees. Employees of large sectors need to improve level of communication to enhance the Job satisfaction and commitment and hence retention in organizations. Without interpersonal communication, there may be lots of issues take place. Management and coordination of different departments in various functions can also be possible with the use of systematic interpersonal communication system. A good interpersonal skills are always proved important for employees in making organizations successful and it affects different elements of organizational effectiveness.