High-efficiency rock breaking by hydraulic jetting is the key to radial horizontal drilling technology. In order to improve the drilling efficiency of hydraulic jet rock breaking in radial horizontal wells, based on LS-Dyna display dynamics, a numerical simulation model of single-nozzle jet rock breaking was established to analyze the influence of different nozzle parameters on the rock-breaking effect. Then, the numerical simulation model of the spin multi-nozzle jet bit was established, and the influence of different rotation speeds on the rock-breaking effect of the jet bit was analyzed. Finally, the rock-breaking drilling characteristics of the spin multi-nozzle jet bit and the conventional multi-nozzle jet bit were compared and analyzed. The results show that when the jet impacts the rock surface, the larger the inclination angle is, the larger the rock-breaking width formed by the jet is. The smaller the dip angle, the greater the rock-breaking depth. When the inclination angle is greater than 60°, it is difficult to meet the needs of reaming. The width and depth of the nozzle gradually increase with the increase of the diameter. When the nozzle diameter is greater than 1.3 mm, the growth rate of rock-breaking depth begins to decrease. The optimum nozzle diameter is 1.3 mm. When v = 50 m/s, the damage caused by the jet to the rock surface is very small, because the condition of rock fracture is not reached with this velocity. This shows that there is a critical value of the water jet impact velocity, and only when the velocity is reached, will the rock break. When the velocity is v = 150 m/s, v = 200 m/s, v = 250 m/s, v = 300 m/s, the rock breaks. At the same time, the higher the speed, the higher the degree of rock fracture, the greater the fracture depth, the greater the fracture area, and the better the fracture effect. The tangential and radial velocity of the jet increases the shear and tensile failure rate of the sample, and improves the rock-breaking efficiency of the jet, which has a certain guiding significance for improving the rock-breaking drilling efficiency of radial horizontal well drilling.