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Molecules
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Molecules
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Interleukin-33: Its Emerging Role in Allergic Diseases

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 09 Jul 2018 English Publisher:MDPI AGJournal:Molecules, volume 23, page 1,665 (eissn: 1420-3049, Copyright policy )
Authors: Wen Ding; Gui-Lin Zou; Wei Zhang; Xing-Ning Lai; Hou-Wen Chen; Li-Xia Xiong;

doi: 10.3390/molecules23071665

pmid: 29987222

pmc: PMC6099536

Interleukin-33: Its Emerging Role in Allergic Diseases

Abstract

Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.

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Keywords

allergic diseases, Th2-type immunity, target therapy, interleukin-33, Organic chemistry, Review, asthma, Interleukin-33, Interleukin-1 Receptor-Like 1 Protein, Up-Regulation, QD241-441, Th2 Cells, Hypersensitivity, Quality of Life, Humans, Signal Transduction

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 65
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
65
Top 10%
Top 10%
Top 1%
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gold
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