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Bioactive Phenylpropanoid Glycosides from Tabebuia avellanedae

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 24 Jun 2013 English Publisher:MDPI AGJournal:Molecules, volume 18, pages 7,336-7,345 (eissn: 1420-3049, Copyright policy )
Authors: Fumihide Takano; Shouwen Jin; Tomihisa Ohta; Maorong Suo;

doi: 10.3390/molecules18077336

pmid: 23797703

pmc: PMC6270160

Bioactive Phenylpropanoid Glycosides from Tabebuia avellanedae

Abstract

Three novel phenylpropanoid glycosides 2, 5, 6 were isolated from water extract of Tabebuia avellanedae, together with three known phenylpropanoid glycosides 1, 3, 4. All compounds were identified on the basis of spectroscopic analysis and chemical methods and, for known compounds, by comparison with published data. All isolated compounds showed strong antioxidant activity in the DPPH assay, and compound 5 give the highest antioxidant activity among all compounds, with an IC50 of 0.12 µM. All compounds exhibited moderate inhibitory effect on cytochrome CYP3A4 enzyme.

Related Organizations
Keywords

<i>Tabebuia avellanedae</i> Lorentz ex Griseb; phenylpropanoid glycosides; antioxidant activity, Tabebuia avellanedae Lorentz ex Griseb, Plant Extracts, Propanols, antioxidant activity, Organic chemistry, Free Radical Scavengers, Tabebuia, Article, Antioxidants, QD241-441, Plant Bark, Cytochrome P-450 CYP3A Inhibitors, Glycosides, phenylpropanoid glycosides

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 19
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Average
Green
gold