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Molecules
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Molecules
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Molecules
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A New Triterpenoid Saponin from Abrus precatorius Linn

Authors: Si Zhang; Cai-Guo Huang; Chuan-Rong Li; Zhi-Hui Xiao; Fa-Zuo Wang; Ai-Jun Sun;

A New Triterpenoid Saponin from Abrus precatorius Linn

Abstract

A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.

Keywords

Cell Survival, Plant Extracts, Organic chemistry, Saponins, Antineoplastic Agents, Phytogenic, Article, Triterpenes, Inhibitory Concentration 50, QD241-441, Abrus precarorius Linn, Cell Line, Tumor, Abrus, cytotoxicity, Humans, triterpenoid, Oleanolic Acid, <em>Abrus precarorius </em>Linn; triterpenoid; saponin; cytotoxicity, saponin

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
26
Top 10%
Top 10%
Top 10%
Green
gold