
A new triterpenoid saponin, 3-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl subprogenin D (1), together with six known triterpenoids: subprogenin D (2), abrusgenic acid (3), triptotriterpenic acid B (4), abruslactone A (5), abrusogenin (6) and abrusoside C (7) were isolated from the leaves and stems of Abrus precatorius. Their structures were elucidated on the basis of physical and NMR analysis, respectively. Compounds 5 and 6 showed moderate cytotoxicity against MCF-7, SW1990, Hela, and Du-145 cell lines. Compounds 1, 2 and 4 were isolated from this plant for the first time.
Cell Survival, Plant Extracts, Organic chemistry, Saponins, Antineoplastic Agents, Phytogenic, Article, Triterpenes, Inhibitory Concentration 50, QD241-441, Abrus precarorius Linn, Cell Line, Tumor, Abrus, cytotoxicity, Humans, triterpenoid, Oleanolic Acid, <em>Abrus precarorius </em>Linn; triterpenoid; saponin; cytotoxicity, saponin
Cell Survival, Plant Extracts, Organic chemistry, Saponins, Antineoplastic Agents, Phytogenic, Article, Triterpenes, Inhibitory Concentration 50, QD241-441, Abrus precarorius Linn, Cell Line, Tumor, Abrus, cytotoxicity, Humans, triterpenoid, Oleanolic Acid, <em>Abrus precarorius </em>Linn; triterpenoid; saponin; cytotoxicity, saponin
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