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Publication . Article . Other literature type . 2017

Anti-Biofilm Effect of Biodegradable Coatings Based on Hemibastadin Derivative in Marine Environment

Tiffany Le Norcy; Hendrik Niemann; Peter Proksch; Isabelle Linossier; Karine Vallée-Réhel; Claire Hellio; Fabienne Faÿ;
Open Access
Published: 01 Jul 2017 Journal: International Journal of Molecular Sciences, volume 18, page 1,520 (eissn: 1422-0067, Copyright policy )
Publisher: MDPI AG
Country: France
International audience; Dibromohemibastadin-1 (DBHB) is an already known potent inhibitor of blue mussel phenoloxidase (which is a key enzyme involved in bioadhesion). Within this study, the potentiality of DBHB against microfouling has been investigated. The activity of DBHB was evaluated on key strains of bacteria and microalgae involved in marine biofilm formation and bioassays assessing impact on growth, adhesion and biofilm formation were used. To assess the efficiency of DBHB when included in a matrix, DBHB varnish was prepared and the anti-microfouling activity of coatings was assessed. Both in vitro and in situ immersions were carried out. Confocal Laser Scanning Microscopy (CLSM) was principally used to determine the biovolume and average thickness of biofilms developed on the coatings. Results showed an evident efficiency of DBHB as compound and varnish to reduce the biofilm development. The mode of action seems to be based principally on a perturbation of biofilm formation rather than on a biocidal activity in the tested conditions.
Subjects by Vocabulary

Microsoft Academic Graph classification: Biofilm Marine bacteriophage Chemical engineering Anti biofilm Bacteria biology.organism_classification biology Microbiology Biofouling Confocal laser scanning microscopy Bioassay Varnish visual_art.visual_art_medium visual_art Chemistry

Library of Congress Subject Headings: lcsh:Biology (General) lcsh:QH301-705.5 lcsh:Chemistry lcsh:QD1-999


Inorganic Chemistry, Organic Chemistry, Physical and Theoretical Chemistry, Computer Science Applications, Spectroscopy, Molecular Biology, General Medicine, Catalysis, antifouling, biodegradable coating, hemibastadin, sponges, marine bacteria, microalgae, ACL, [SDV]Life Sciences [q-bio], [SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere, antifouling, biodegradable coating, hemibastadin, sponges, marine bacteria, microalgae, antifouling; biodegradable coating; hemibastadin; sponges; marine bacteria; microalgae, Article