Searching the Pubmed, HINARI and Scielo meta-searches with the terms "prophylaxis" "Hydroxychloroquine" and "COVID-19" linked by the Boolean operator AND, the terms Chloroquine" "prophylaxis" and "COVID-19", linked by the Boolean operator AND, were also used. Thesearch for the term "Hydroxychloroquine" yielded no results, while the search for the term "Chloroquine" yielded 2 publications in Hinari, ofwhich 1 was discarded for not mentioning the use of chloroquine (or hydroxychloroquine) as a therapeutic alternative. With respect to use asprophylaxis to prevent SARS-CoV-2 infection with CQ or HCQ, we have no evidence to extrapolate or even recommend a scheme for such purposes.