publication . Article . 2019

Current Approaches to Valerian Tincture Standardisation in Terms of Assay

Antonova, N. P.; Shefer, E. P.; Kalinin, A. M.; Semenova, N. E.; Prokhvatilova, S. S.; Morgunov, I. M.;
Open Access Russian
  • Published: 03 Dec 2019 Journal: Ведомости Научного центра экспертизы средств медицинского применения, volume 9, issue 4, pages 265-271 (issn: 1991-2919, eissn: 2619-1172, Copyright policy)
  • Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”
Abstract
The quality control of the «Valerian rhizome and roots» herbal substance is carried out using high performance liquid chromatography (HPLC) according to the State Pharmacopoeia of the Russian Federation, XIV edition. The quantitative analysis of the active ingredients in valerian tincture is performed using a non-specific and non-selective spectrophotometric method. Therefore, it is important to introduce in Russia a more modern test procedure for quantitative determination of active ingredients in valerian tincture.The aim of the study was to develop a selective and sensitive HPLC procedure for quantitative determination of the total content of sesquiterpenic a...
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free text keywords: tincture, valerian, hplc, valerenic acid, acetoxyvalerenic acid, pharmacopoeial methods, tinctura valerianae, lcsh:Medicine (General), lcsh:R5-920, Pharmacopoeia, law.invention, law, Valerian, biology.organism_classification, biology, High-performance liquid chromatography, Valerenic acid, chemistry.chemical_compound, chemistry, Quantitative analysis (chemistry), Active ingredient, Spectrophotometry, medicine.diagnostic_test, medicine, Reference standards, Chromatography
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