publication . Article . 2018

A METHODOLOGICAL APPROACH TO DESIGNING EXPERIMENTS WHEN DEALING WITH IDENTIFICATION TESTS FOR MEDICINAL PRODUCT COMPONENTS (AS ILLUSTRATED BY ASCORBIC ACID)

Purim, Yu. B.; Kruglyakova, M. L.; Bulanova, L. N.; Agapkina, M. V.; Stronova, L. N.; Bokovikova, T. N.; Gernikova, E. P.;
Open Access Russian
  • Published: 26 Sep 2018 Journal: Ведомости Научного центра экспертизы средств медицинского применения, volume 8, issue 3, pages 193-200 (issn: 1991-2919, eissn: 2619-1172, Copyright policy)
  • Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”
Abstract
The need for identification testing of active substances or excipients in multi-component medicinal products, including the use of qualitative tests, calls for research substantiating the choice of tests and test conditions with due regard to interference effects caused by other components of medicinal products and the amount of the sample used. The aim of the study was to develop a methodological approach to designing experiments while selecting qualitative reactions for identification testing of a medicinal product component based on the results of studies investigating the possibility of using known qualitative tests (as illustrated by ascorbic acid in a mult...
Persistent Identifiers
Subjects
free text keywords: methodological approach, qualitative reactions, test conditions, ascorbic acid, antioxidant, parenterals, Medicine (General), R5-920, Reagent, Antioxidant, medicine.medical_treatment, medicine, Iodine test, Chemistry, Experimental testing, Silver nitrate, chemistry.chemical_compound, Ascorbic acid, Chemical reaction, Potassium permanganate, Chromatography
Any information missing or wrong?Report an Issue