publication . Article . 2021

Improvement of Methods of Standardisation of Medicinal Products Made from Veratrum Lobelianum Rhizomes with Roots

N. P. Antonova; I. M. Morgunov; S. S. Prokhvatilova; E. P. Shefer; O. V. Evdokimova; A. V. Beketova; M. N. Lyakina;
Open Access Russian
  • Published: 01 Mar 2021 Journal: Ведомости Научного центра экспертизы средств медицинского применения, volume 11, issue 1, pages 44-48 (issn: 1991-2919, eissn: 2619-1172, Copyright policy)
  • Publisher: OOO “Vashe Tsifrovoe Izdatelstvo”
Abstract. Identification of hellebore (Veratrum Lobelianum Bernh.) herbal substance, as well as hellebore-based herbal preparation and herbal medicinal product by the same group of biologically active substances using the same test method is in line with the so-called “consistent standardisation” principle.The aim of the study was to develop a harmonised approach to identification of steroidal alkaloids in hellebore products (hellebore water, hellebore tincture) and hellebore herbal substance (hellebore rhizomes with roots).Materials and methods: samples of hellebore water, hellebore tincture, and hellebore rhizomes with roots were analysed by high-performance t...
free text keywords: steroidal alkaloids, hptlc, hellebore rhizomes with roots, medicines, рharmacopoeial monographs, Medicine (General), R5-920
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