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LÍQUEN ESCLEROSO EXTRAGENITAL EM CRIANÇA COM BOA RESPOSTA À COLCHICINA

Authors: Juliana Salvini Barbosa Martins da Fonseca; Aline Godinho Ferreira Silva; Mariana Gardone Guimarães; Paôlla Alves de Faria; Fred Bernardes Filho;

LÍQUEN ESCLEROSO EXTRAGENITAL EM CRIANÇA COM BOA RESPOSTA À COLCHICINA

Abstract

 O líquen escleroso é uma doença inflamatória crônica, de origem multifatorial envolvendo fatores genéticos,fisiológicos e ambientais. Geralmente acomete mulheres, entre 50-60 anos, na variante genital. Sendo incomumem crianças e na forma extragenital. É aceita como uma desordem autoimune, mas seu mecanismo permanece indefinido.O relato apresentado flama a atenção quanto a variante extragenital, exibindo localização incomum de ser acometida.Relatamos o caso de uma criança com apresentação extragenital de localização incomum, região femoral.Paciente fez uso de outras medicações, mas teve melhora do quadro após o uso de colchicina tópica. Esta medicação tem boa absorção via tópica e tem a capacidade de inibir a divisão celular. Além de ter a ação anti-inflamatória, pois diminui a mobilidade, a adesividade e a quimiotaxia dos polimorfonucleares sobre a desgranulação dos lisossomos.

Related Organizations
Keywords

Colchicina, RL1-803, Líquen escleroso, Criança, Extragenital, Dermatology, Infectious and parasitic diseases, RC109-216

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Published in a Diamond OA journal
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