publication . Article . Other literature type . Part of book or chapter of book . 2012

PULMONARY ARTERIAL HYPERTENSION IN CONNECTIVE TISSUE DISEASES

Bruno Dino Bodini; Simona Sitia; Livio Tomasoni; Matteo Longhi; Maurizio Turiel;
Open Access
  • Published: 30 Jun 2012 Journal: Rheumatology Science and Practice (issn: 1995-4484, eissn: 1995-4492, Copyright policy)
  • Publisher: Mediar Press
Abstract
Pulmonary arterial hypertension (PAH) is a progressive disease caused by a remodeling of precapillary arterioles that leads to a progressive increase in pulmonary vascular resistance and right ventricular failure. PAH is associated with significant morbidity and mortality, despite the advent of specific therapies that target pathobiologic pathways implicated in the disease process [1–3]. PAH is can only be diagnosed by right heart catheterization (RHC) and is defined as a mean pulmonary artery pressure greater than 25 mmHg in the absence of elevation of the pulmonary capillary wedge pressure. PAH includes a heterogeneous group of clinical entities sharing simila...
Subjects
free text keywords: Cardiology and Cardiovascular Medicine, General Medicine, connective tissue diseases, corticosteroid, doppler echocardiography, mixed connective tissue disease, pulmonary hypertension, Article, pulmonary arterial hypertension, systemic sclerosis, Pulmonary and Respiratory Medicine, Differential diagnosis, Poor prognosis, Central hemodynamics, Intensive care medicine, medicine.medical_specialty, medicine, business.industry, business, Pharmacotherapy, Connective tissue, medicine.anatomical_structure, Dermatomyositis, medicine.disease, Pathology, Systemic lupus erythematosus, CTD, Pulmonary wedge pressure, Heart failure, Vascular resistance, Pulmonary artery, medicine.artery, Connective tissue disease, Mixed connective tissue disease, Portopulmonary hypertension, Pulmonary hypertension, Cardiology, Complication, Internal medicine, Polymyositis, Blood pressure, Doppler echocardiography, medicine.diagnostic_test, Cause of death, Surgery, lcsh:Immunologic diseases. Allergy, lcsh:RC581-607, lcsh:Diseases of the musculoskeletal system, lcsh:RC925-935

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