ODGKIN'S disease is the best known member of a group of malignant lymphomas, which includes lymphosarcoma, reticulum cell sarcoma, and follicular lymphoblastoma or Brill-Symmer's disease. The diagnosis can be made only by microscopic examination of a biopsied lymph node since the clinical course of these various lymphomas is quite similar, and since relatively benign lesions, such as tuberculous lymphadenopathy, Boeck's sarcoid, and other chronic inflammatory lesions, may simulate malignant lymphoma. Even the biopsy may prove difficult for the pathologist to interpret and, in many cases, must be repeated in order to obtain a definitive diagnosis. Furthermore, Custer and others have called attention to the fact that