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The Immunodepressive Effect of Infectious Bursal Disease Virus in Chickens

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1974Publisher:JSTORJournal:Avian Diseases, volume 18, page 50 (issn: 0005-2086,

Authors: S. Shimakura; F Taguchi; Katsuya Hirai; S T Kim; C N Chang; Y Iritani; E. Kawamoto;

doi: 10.2307/1589241

pmid: 4360708

The Immunodepressive Effect of Infectious Bursal Disease Virus in Chickens

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Abstract

SUMMARY Infectious bursal disease virus (IBVD) depressed the humoral antibody response of chickens to various vaccines. The virus had that effect whether injected at the same time as vaccination or 4 or 7 days before. The depression was slightly greater when injection was 7 days before, and was most pronounced in chickens inoculated with IBDV when 6 weeks old, slight in 4-week-olds, and absent in 2-week-olds. Protection against challenge by virulent ND virus 3 weeks after ND vaccination showed the marked differences between IBDV-inoculated and uninoculated chickens.

Keywords

Immunosuppression Therapy, Immunodiffusion, Haemophilus, Newcastle disease virus, Viral Vaccines, Hemagglutination Inhibition Tests, Reoviridae, Reoviridae Infections, Bursa of Fabricius, Salmonella, Agglutination Tests, Antibody Formation, Bacterial Vaccines, Animals, Chickens, Poultry Diseases

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	97
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 1%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%