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Nihon Naika Gakkai Zasshi
Article . 1968 . Peer-reviewed
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Nihon Naika Gakkai Zasshi
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Nihon Naika Gakkai Zasshi
Article . 1968
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STUDIES ON RENAL CIRCULATION THE RENAL HEMODYNAMICS IN HYPOXIA

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1968 English Publisher:Japanese Society of Internal MedicineJournal:Nihon Naika Gakkai Zasshi, volume 57, pages 57-69 (issn: 0021-5384, eissn: 1883-2083, Copyright policy )
Authors: Nobushige Ote;

doi: 10.2169/naika.57.57

pmid: 5690948

STUDIES ON RENAL CIRCULATION THE RENAL HEMODYNAMICS IN HYPOXIA

Abstract

低酸素時の腎循環調節機構を解明するため, pentobarbital sodiumで麻酔した雑種成熟イヌ41頭を用い,低酸素負荷(5%O2•95%N2, 5分間)時の腎旗行動態の変動を研究した.腎神経保存イヌでは低酸素負荷により体血圧の上昇, RBFの減少およびRVRの増大を認めたが,腎神経切断イヌではRVR増大が遅れかつ軽度であつた.自律神経節遮断イヌでは腎血行動態に有意の変化を生じなかつた.一方,体外循環により定圧で左腎を潅流した場合は,低酸素負荷により体血圧上昇, RBF減少, RVRの軽度増大を示した. C6•dibenamineで腎外性因子を遮断したイヌでは, RBFは増加しRVRは有意の減少を示した.腎を静脈血で潅流したさいも同様の結果が認められた.従つて5%02吸入時の腎循環の変動は,低酸素血自体が腎血管に対して拡張作用を有するにもかかわらず,主として交感神経性,一部体液性支配に基づぎ,体血圧上昇と同時に腎血管収縮をもたらすものと考えられる.

Related Organizations
Keywords

Male, Oxygen, Dogs, Regional Blood Flow, Papaverine, Hemodynamics, Animals, Female, Hypoxia, Kidney

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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