This work intends to demonstrate the importance of Artificial Intelligence (AI) implementation in the trucking industry and to present Autonomous Vehicles (AV) technology as one that is rapidly emerging. The work will start with a brief introduction of AV technology and its current position in America. After the short overview of the size (and structure) of the trucking industry in the USA, it will be explained what role is expected AV to play in the industry and what it would be able to offer to supply chains. This paper will show the necessity for the integration of AV technology within the trucking industry in the USA.