publication . Article . Other literature type . 2017

SIMULATION OF TARGETED TRANSPORT FOR DRUG SUBSTANCES PART 1: A SINGLE ADMINISTRATION

A. V. Zaborovskiy; K. G. Gurevich;
Open Access
  • Published: 01 Mar 2017 Journal: Siberian journal of oncology, volume 16, pages 59-65 (issn: 1814-4861, eissn: 2312-3168, Copyright policy)
  • Publisher: Tomsk Cancer Research Institute
Abstract
In oncology practice, despite advances in methods for early detection, surgery, radiotherapy, laser therapy, targeted therapy, etc., chemotherapy is unlikely to lose its relevance in the near future. In this context, the development of new antitumor drugs is one of the urgent problems of modern conservative oncology. Despite the importance of the search for new compounds with antitumor activity, the clinical potential of the «old» agents does not yet seem to be exhausted. The transport of antitumor agents can give them a «second life» in the clinic. When developing the targeted transport for chemotherapeutic drugs, the changes in their pharmacodynamics and pharm...
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free text keywords: drugs, targeted transport, target tissue, antitumor drugs, Pharmacology, Drug, media_common.quotation_subject, media_common, Medicine, business.industry, business, Single administration, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, lcsh:RC254-282
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