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University of California: eScholarship
Article . 2022
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Aging
Article . 2022 . Peer-reviewed
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Aging
Other literature type . 2022
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Article . 2022
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Article . 2022
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T cell senescence by N-glycan branching

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 13 Aug 2022 United States English Publisher:Impact Journals, LLCJournal:Aging, volume 14, pages 5,964-5,965 (eissn: 1945-4589, Copyright policy )
Authors: Mkhikian, Haik; Demetriou, Michael;

doi: 10.18632/aging.204239

pmid: 35963641

pmc: PMC9417233

T cell senescence by N-glycan branching

Abstract

Immune-senescence refers to the aging of the immune system and the resulting deterioration in its ability to fight infections and cancer in older individuals. This phenomenon is reflected in the numerous infectious diseases which show increased severity in the elderly, most recently demonstrated by the COVID-19 pandemic. The trajectory of the COVID-19 pandemic would have differed markedly if the severity of disease in older individuals was similar to healthy young individuals. Therefore, understanding what factors contribute to immune-senescence and how to reverse them is of great importance

Country
United States
Related Organizations
Keywords

Biomedical and Clinical Sciences, interleukin-7, T-Lymphocytes, Clinical Sciences, T cell, Clinical sciences, Biological Sciences, N-acetylglucosamine, N-Acetylglucosaminyltransferases, immune-senescence, Editorial, Polysaccharides, Biochemistry and cell biology, Biochemistry and Cell Biology, Cellular Senescence, N-glycan branching

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    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 1
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Average
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
Green
gold
Related to Research communities
Corona Virus Disease
Cancer Research