Renal cell carcinoma (RCC) accounts for more than eighty-five percent of primary renal cell carcinomas with male preponderance in 5 to 7 decades. Collecting duct carcinoma (CDC) constitutes for less than 1% of all renal cell carcinomas. Histopathological examination of all types of RCC is almost importance in view of therapeutic and prognostic implications of its varied subtypes. The purpose of this editorial is to highlight the morphology and rarity of collecting duct carcinoma and differentiation of it from papillary renal cell carcinoma.