publication . Article . 2018

Chronic pain, depression and cognitive impairment: a close relationship

Latysheva, N. V.; Filatova, E. G.; Osipova, D. V.;
Open Access Russian
  • Published: 26 Oct 2018 Journal: Nervno-Myšečnye Bolezni, volume 8, issue 3, pages 34-42 (issn: 2222-8721, eissn: 2413-0443, Copyright policy)
  • Publisher: ABV-press
Abstract
Over a half of chronic pain (CP) patients present with cognitive complaints, which increase their disability and impact quality of life. The paper reviews objective impairments in memory, attention, processing speed and executive function demonstrated in the CP population. The paper also reviews common pathology underlying cognitive impairment and CP: neuroplasticity in the shared brain areas, neurotransmitter and other molecular mechanisms. Common mechanisms in CP and depression precipitating cognitive impairment are also discussed. The paper also compares the potential of different antidepressants to improve cognitive functions in depression and CP.
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Subjects
free text keywords: chronic pain, depression, cognitive impairment, memory, attention, Neurology. Diseases of the nervous system, RC346-429, Clinical Neurology, Neurology, Cognition, Quality of life, Chronic pain, medicine.disease, medicine, Cognitive impairment, business.industry, business, Clinical psychology, Population, education.field_of_study, education, Neuroplasticity
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