publication . Article . 2020

Overview of anticonvulsant therapy in full-term and premature neonates

M. A. Ivzhits; S. K. Zyryanov; G. V. Rodoman; I. B. Bondareva; S. V. Dumova; O. A. Babak; M. S. Chenkurov; G. A. Putsman;
Open Access Russian
  • Published: 01 Sep 2020 Journal: Russkij Žurnal Detskoj Nevrologii, volume 15, issue 2, pages 42-54 (issn: 2073-8803, eissn: 2412-9178, Copyright policy)
  • Publisher: ABV-press
<jats:p>Convulsions in full-term and especially in premature newborns are observable pathologies. Selection of anticonvulsant therapy is very difficult:<jats:italic> </jats:italic>newborns have particular pharmacokinetics of drugs, insufficient data on doses and therapeutic concentrations of anticonvulsants in the blood<jats:italic> </jats:italic>(premature infants mainly). This article is an overview, with an emphasis on the features of dosing and pharmacokinetics of anticonvulsants<jats:italic> </jats:italic>in term and preterm infants.</jats:p>
Persistent Identifiers
free text keywords: full-term and premature newborns, convulsions, anticonvulsants, dosing regimen, pharmacokinetics, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429, Dosing, Pharmacology, Anticonvulsant therapy, Medicine, business.industry, business
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