publication . Article . 2017

JUVENILE MYOCLONIC EPILEPSY: FOCUS ON THE USE OF TOPIRAMATE (LITERATURE REVIEW AND OWN DATA)

K. Yu. Mukhin; O. A. Pylaeva;
Open Access Russian
  • Published: 01 Aug 2017 Journal: Russkij Žurnal Detskoj Nevrologii, volume 12, issue 2, pages 8-20 (issn: 2073-8803, eissn: 2412-9178, Copyright policy)
  • Publisher: ABV-press
Abstract
Juvenile myoclonic epilepsy (JME) is an inherited genetic syndrome within the group of idiopathic generalized epilepsies (IGE). The disease is characterized by an adolescence-onset with massive myoclonic seizures often combined with generalized convulsive seizures and absence seizures and by typical changes in the electroencephalogram appearing as short generalized polyspike-and-wave epileptiform discharges with a frequency of 3–6 Hz. Despite the high rate of remission (75–85 %) in patients receiving adequate therapy, this form of epilepsy brings more significant inconveniences for patients than many other forms of IGE. Such factors as violation of sleep hygiene...
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free text keywords: epilepsy, idiopathic generalized epilepsy, juvenile myoclonic epilepsy, diagnosis, treatment, topiramate, remission, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429, Epilepsy, medicine.disease, medicine, Tolerability, Valproic Acid, medicine.drug, Idiopathic generalized epilepsy, Topiramate, Pediatrics, medicine.medical_specialty, Sleep hygiene, Juvenile myoclonic epilepsy, Anesthesia, Disease, business.industry, business
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