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Publication . Article . 2021

Hereditary breast cancer and ovarian cancer: clinical course and treatment

V. V. Semiglazov; A. Е. Protasova; G. K. Kalikeev;
Open Access  
Published: 13 Mar 2021 Journal: Tumors of female reproductive system, volume 16, pages 54-65 (issn: 1994-4098, eissn: 1999-8627, Copyright policy )
Publisher: Publishing House ABV Press
Abstract
This article analyzes current problems associated with surgical and systemic treatment for hereditary breast and ovarian cancers (including those associated with BRCA1/2 gene mutations). We discuss the issues related to clinical course of multiple primary tumors and their sensitivity to cytostatic and targeted therapy.
Subjects by Vocabulary

Microsoft Academic Graph classification: Oncology medicine.medical_specialty medicine business.industry business Targeted therapy medicine.medical_treatment Breast cancer medicine.disease Internal medicine Gene mutation CHEK2 Ovarian cancer Clinical course

Medical Subject Headings: skin and connective tissue diseases endocrine system diseases

Subjects

Pharmacology (medical), Obstetrics and Gynecology, Radiology, Nuclear Medicine and imaging, Oncology, Surgery, breast cancer, ovarian cancer, multiple primary tumors, brca1, brca2, chek2, parp inhibitors, Gynecology and obstetrics, RG1-991