publication . Article . 2018

Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in patients with early-stage breast cancer

Elena M. Slonimskaya; A. V. Doroshenko; Polina Kazantseva; N. A. Tarabanovskaya; R. Yu. Vernadsky;
Open Access Russian
  • Published: 16 Oct 2018 Journal: Opuholi Ženskoj Reproduktivnoj Sistemy, volume 14, issue 3, pages 48-54 (issn: 1994-4098, eissn: 1999-8627, Copyright policy)
  • Publisher: ABV-press
Abstract
Adjuvant hormone therapy is considered the gold standard of therapy for hormone receptor-positive operable breast cancer. The approach to adjuvant hormone therapy in premenopausal patients has changed significantly in recent years. This change was caused by clinical trials, which have confirmed the advantage of adding ovarian suppression to tamoxifen or aromatase inhibitors monotherapy. Individual approach to choosing an appropriate regimen of adjuvant hormone therapy in premenopausal patients with breast cancer should be based on the assessment of risks for relapse, expected effectiveness of treatment and evaluation of drug safety.
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Medical Subject Headings: skin and connective tissue diseases
free text keywords: breast cancer, hormone therapy, ovarian suppression, gonadotropin-releasing hormone analogues, tamoxifen, exemestane, Gynecology and obstetrics, RG1-991, Breast cancer, medicine.disease, medicine, Aromatase, biology.protein, biology, Internal medicine, medicine.medical_specialty, Exemestane, chemistry.chemical_compound, chemistry, Tamoxifen, medicine.drug, Adjuvant, medicine.medical_treatment, Hormone therapy, Oncology, Regimen, business.industry, business, Clinical trial
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