publication . Article . 2019

The study of oncolytic viruses reproduction in organ cultures of human lymphoid tumors

Babaeva, F. E.; Lipatova, A. V.; Kochetkov, D. V.; Chumakov, P. M.; Kravchenko, S. K.;
Open Access Russian
  • Published: 22 Dec 2019 Journal: Onkogematologiâ, volume 14, issue 4, pages 84-89 (issn: 1818-8346, Copyright policy)
  • Publisher: ABV-press
Abstract
Oncolytic viruses are promising agents for the treatment of various types of tumors, including malignant non-Hodgkin lymphomas. In order to identify the most effective candidates from a wide panel of non-pathogenic antitumor strains, a study was carried out of their ability to reproduce in short-term cultures of lymphoid tumor cells. Also, tumor cell cultures were characterized in relation to the presence of specific viral receptors CD54, CD55, CD155 on their surface.
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Subjects
Medical Subject Headings: hemic and lymphatic diseases
free text keywords: oncolytic viruses, lymphomas, chemotherapy, immunotherapy, cell cultures, Diseases of the blood and blood-forming organs, RC633-647.5, Receptor, Cancer research, CD155, biology.protein, biology, Immunotherapy, medicine.medical_treatment, medicine, Chemotherapy, Oncolytic virus, Cell culture, Lymphoid Tumor, Tumor cells
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