publication . Article . 2019

The experience of free light chains of immunoglobulin elimination in patients with monoclonal gammopathies

Gromova, E. G.; Zeynalova, P. A.; Lubimova, N. V.; Timofeev, Yu. S.; Kushlinskiy, N. E.; Semenova, A. A.; Lunin, V. V.; Kluchagina, Yu. I.;
Open Access
  • Published: 26 Jul 2019 Journal: Oncohematology, volume 14, pages 8-12 (issn: 1818-8346, eissn: 2413-4023, Copyright policy)
  • Publisher: Publishing House ABV Press
Abstract
The objective of study is to estimate the efficiency of extracorporeal free light chains of immunoglobulin elimination in patients with monoclonal gammopathies (n = 12) during hemodialysis using selective filters.Materials and methods. A blood and dialysate free light chains concentrations change was criterion of efficiency.Results and conclusion. The selective free light chains filtration give the possibility of an adequate anti-tumor therapy, could prevent the development of irreversible renal failure and hypoalbuminemia.
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Subjects
Medical Subject Headings: genetic structurespsychological phenomena and processesbehavioral disciplines and activitiesnervous system
free text keywords: free light chains of immunoglobulin, monoclonal gammopathies, multiple myeloma, lymphoma, extracorporeal detoxification, Lymphoma, medicine.disease, medicine, Gastroenterology, medicine.medical_specialty, Extracorporeal, Hemodialysis, medicine.medical_treatment, Hypoalbuminemia, Antibody, biology.protein, biology, In patient, Immunoglobulin light chain, Multiple myeloma, Internal medicine, business.industry, business, lcsh:Diseases of the blood and blood-forming organs, lcsh:RC633-647.5
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