publication . Article . 2018

Cutaneous T-cell lymphomas: modern data of pathogenesis, clinics and therapy

Demina, O. M.; Akilov, O. E.; Rumyantsev, A. G.;
Open Access Russian
  • Published: 27 Oct 2018 Journal: Onkogematologiâ, volume 13, issue 3, pages 25-38 (issn: 1818-8346, Copyright policy)
  • Publisher: ABV-press
Abstract
Cutaneous T-cell lymphomas (CTCL) are a heterogeneous group of extranodal non-Hodgkin’s lymphomas that are characterized by skin infiltration with malignant monoclonal T lymphocytes. More common in adults aged 55 to 60 years, the annual incidence is about 0.5 per 100 000 people. Mycosis fungoides, Sézary syndrome and CD30+ lymphoproliferative diseases are the main subtypes of CTCL. To date, CTCL have a complex concept of etiopathogenesis, diagnosis, therapy and prognosis. The article presented summary data on these issues.
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Subjects
Medical Subject Headings: hemic and lymphatic diseasesimmune system diseases
free text keywords: 1cutaneous t-cell lymphomas, gene expression, anticancer treatment, lcsh:Diseases of the blood and blood-forming organs, lcsh:RC633-647.5, Monoclonal, Heterogeneous group, Dermatology, medicine.medical_specialty, medicine, Mycosis fungoides, medicine.disease, Anticancer treatment, Summary data, business.industry, business, Annual incidence, CD30, Skin infiltration
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