publication . Article . Other literature type . 2018

HETEROGENEITY OF CHILDHOOD B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA (EGIL SUBTYPE BIV)

Open Access
  • Published: 08 Feb 2018 Journal: Oncohematology, volume 12, pages 34-40 (issn: 1818-8346, eissn: 2413-4023, Copyright policy)
  • Publisher: Publishing House ABV Press
Abstract
Introduction. Surface immunoglobulin expression is a main immunophenotypic criteria of mature subtype of B-lineage acute lymphoblastic leukemia. Although the majority of such cases represents Burkitt leukemia/lymphoma, it was shown for several times that membrane IgM could be detected in the absence of other mature lymphomas signs. The aim of the study  was to evaluate heterogeneity of childhood acute lymphoblastic leukemia (ALL) with surface IgM expression and to assess correspondence of BIV EGIL ALL subtype with Burkitt lymphoma (BL) bone marrow dissemination. Materials and methods . Immunophenotypic, cytomorfologic and genetic data of 54 BIV-ALL cases were an...
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Subjects
Medical Subject Headings: hemic and lymphatic diseases
free text keywords: burkitt lymphoma/leukemia, acute lymphoblastic leukemia, flow cytometry, Pathology, medicine.medical_specialty, medicine, Heterogeneous group, Leukemia, medicine.disease, KMT2A, biology.protein, biology, Genetic data, Bone marrow, medicine.anatomical_structure, Disease, Childhood Acute Lymphoblastic Leukemia, Lymphoma, business.industry, business, lcsh:Diseases of the blood and blood-forming organs, lcsh:RC633-647.5
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