publication . Part of book or chapter of book . Article . 2006

Myelodysplastic/Myeloproliferative Diseases

Wojciech Gorczyca; James Weisberger; Foxwell Emmons;
Open Access
  • Published: 12 Jan 2006
  • Publisher: SAGE Publications, Inc.
The myelodysplastic/myeloproliferative disorders (MDS/MPD) are a group of hematologic disorders distinguished by clonal expansion of abnormal hematopoietic stem cells that share clinicopathological features of both MDS and chronic myeloproliferative disorders (CMPD). They are characterized by hypercellular bone marrows with excessive terminal proliferation of one or more hematopoietic lineages as well as dysplastic changes. This combination of proliferation and dysplasia may lead to increased production of one or more lineages (cytosis) and decreased production of other lineages simultaneously. According to the WHO classification, these disorders are divided int...
Medical Subject Headings: hemic and lymphatic diseases
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