publication . Article . 2015

Integrated laboratory coagulation tests in hypercoagulation diagnosis and thrombosis risk assessment. Part I. The pathophysiology of thrombosis and hypercoagulation

Lipets, E. N.; Ataullakhanov, F. I.; Panteleev, M. A.;
Open Access Russian
  • Published: 08 Oct 2015 Journal: Onkogematologiâ, volume 10, issue 3, pages 73-77 (issn: 1818-8346, Copyright policy)
  • Publisher: ABV-press
Abstract
Thrombosis is a fatal hemostatic disorders occurring in various conditions ranging from pregnancy and surgery to cancer, sepsis and heart attack. Despite the availability of different anticoagulants and accumulated clinical experience, proving their effectiveness, thrombosis remains a major cause of morbidity and mortality. This is largely due to the fact that conventional laboratory coagulation tests are not sufficiently sensitive to the hypercoagulable state, and they are difficult to use for assessing the risk of thrombosis. Specific molecular markers (D-dimers, fibrinopeptide, thrombin-antithrombin complex) are more effective, but also have a large number of...
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free text keywords: integral coagulation tests, hypercoagulation, thrombosis, d-dimers, fibrinopeptide, antithrombin complex, lcsh:Diseases of the blood and blood-forming organs, lcsh:RC633-647.5
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