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Babesia divergens vaccine

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1992Publisher:FapUNIFESP (SciELO)Journal:Memórias do Instituto Oswaldo Cruz, volume 87, pages 279-281 (eissn: 0074-0276,

Authors: Gorenflot, A.; Precigout, E.; Valentin, A.; Bissuel, G.; Carcy, B.; Brasseur, P.; Moreau, Y.; +1 Authors

doi: 10.1590/s0074-02761992000700047

pmid: 1343703

Babesia divergens vaccine

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Abstract

A vaccine strategy against Babesia divergens bovine babesiosis was successfully developed after perfecting of an efficient in vitro culture. Crude supernatants and purified fractions were able to induce a vaccine protection in gerbils against B. divergens infection. More, supernatants induced an effective vaccine protection in cattle. The role of B. divergens exoantigens of 17, 37, 46, 70 and 90 kDa in the development of the immune response was clearly demonstrated in gerbils, cattle, and man.

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Keywords

Protozoan Vaccines, Vaccination, Babesia, Cattle Diseases, Antigens, Protozoan, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502, exoatingen, Babesia divergens, vaccine, Babesiosis, in vitro culture, Animals, Cattle, Parasitology, Gerbillinae

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