Spray drying and vaccine stabilization

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2012 English Publisher:Informa UK LimitedJournal:Expert Review of Vaccines, volume 11, pages 1,211-1,219 (issn: 1476-0584, eissn: 1744-8395,

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Authors: David, McAdams; Dexiang, Chen; Debra, Kristensen;

doi: 10.1586/erv.12.101

pmid: 23176654

Spray drying and vaccine stabilization

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Abstract

Research on spray drying as a processing method to improve vaccine stabilization and to enable novel routes of vaccine delivery has produced promising results; however, the method has yet to be adopted for the manufacture of vaccine products by the pharmaceutical industry. This article reviews the status of spray-drying technology and discusses barriers and opportunities for its future application to vaccines.

Keywords

Vaccines, Drug Stability, Humans, Technology, Pharmaceutical, Desiccation

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