
Coronary chronic total occlusions (CTOs) still represent the greatest technical challenge that interventional cardiologists face. CTOs remain seriously undertreated with percutaneous techniques, far below their prevalence. One reason for the low uptake was the suboptimal CTO percutaneous coronary intervention (PCI) success rates over a long period of time. During the last years, dedicated groups of experts in Japan, Europe and United States fostered the development and standardisation of modern CTO recanalisation techniques, along with providing focused training and proctorship worldwide. As a result, dedicated operators achieved success rates far beyond 90 %, while coping with lesions of increasing complexity. A series of studies, mainly retrospective and observational in nature, explored the prognostic impact of CTO PCI, revealing that successful lesion recanalisation is related to improved patient outcome and anginal status; further evidence from randomised trials is on the way. The following review reports on the most recent advances in the field of CTO recanalisation, in an attempt to promote a more balanced approach in patients with chronically occluded coronary arteries and encourage more operators to cope with these inherently complex lesions.
Collateral circulation; Coronary chronic total occlusion (CTO); J-CTO; Prognostic benefit; Retrograde approach; Subintimal space; True lumen re-entry; Cardiology and Cardiovascular Medicine, Coronary chronic total occlusion (CTO); J-CTO; collateral circulation; prognostic benefit; retrograde approach; subintimal space; true lumen re-entry
Collateral circulation; Coronary chronic total occlusion (CTO); J-CTO; Prognostic benefit; Retrograde approach; Subintimal space; True lumen re-entry; Cardiology and Cardiovascular Medicine, Coronary chronic total occlusion (CTO); J-CTO; collateral circulation; prognostic benefit; retrograde approach; subintimal space; true lumen re-entry
| selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | 6 | |
| popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network. | Average | |
| influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically). | Average | |
| impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network. | Average |
