
pmid: 3822662
To the Editor.— Notterman et al (Pediatrics 1986;77:850-852) reported about an 8-month-old infant who absorbed crushed isoniazid in applesauce poorly both during treatment for tuberculous meningitis and later in pharmacokinetic studies. A second child exhibited a less severe malabsorption. The authors state that "Children should not be treated with untested ad hoc preparations of drugs. Common practice and textbook recommendations based on such practice may be seriously misleading." I believe that is an unjustified condemnation of a longstanding practice.
Intestinal Absorption, Fruit, Tuberculosis, Meningeal, Isoniazid, Administration, Oral, Humans, Infant
Intestinal Absorption, Fruit, Tuberculosis, Meningeal, Isoniazid, Administration, Oral, Humans, Infant
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