publication . Article . Other literature type . 2016

Sorbents for Extracorporeal Removal of Toxic Substances and Molecules with Adverse Biological Activity (Review)

Morozov, A. S.; Bessonov, I. V.; Nuzhdina, A. V.; Pisarev, V. M.;
Open Access Russian
  • Published: 01 Jan 2016 Journal: Obŝaâ Reanimatologiâ, volume 12, issue 6, pages 82-107 (issn: 1813-9779, eissn: 2411-7110, Copyright policy)
  • Publisher: Russian Academy of Medical Sciences
Abstract
The review devoted to sorbents and sorbentbased medical devices used in clinical practice for extracorporeal detoxification using a hemoperfusion technique. Clinical data have confirmed the effectiveness of this approach for removal of bacterial endotoxins, lowdensity lipoproteins, and bilirubin. Other studies demonstrated successful application of sorbents to treat autoimmune diseases. Special attention is paid to hemoperfusion in as a possible treatment for severe sepsis and septic shock. The review justifies importance of development and application of novel multimodal sorbents, which combine both properties of selective and nonselective sorbents. The review ...
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Subjects
free text keywords: sorbent, plasmasorbent, hemoperfusion, absorbing polymer material, sepsis, extracorporeal therapy, lcsh:Medical emergencies. Critical care. Intensive care. First aid, lcsh:RC86-88.9, Clinical efficacy, Critical illness, Clinical Practice, Molecular interactions, Septic shock, medicine.disease, medicine, Intensive care medicine, medicine.medical_specialty, Hemoperfusion, medicine.medical_treatment, business.industry, business, Sepsis, Severe sepsis
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