This text is an attempt to conduct a historical-materialist analysis of theological, political, and scientific concepts (e.g.,katechon, multitude and vacuum). Such studies carried out in detail on the discussions between Spinoza, Hobbes and Boyle held on the verge of the modern era are to show the crucial theoretical conclusions fraught with consequences. It presents the shaping of the bourgeois vision of science, theology, and the birth of the modern concept of private property on the one hand, and on the other - the forming of the first universalist class struggles conducted both at the level of theology, politics, and the methodology of science. A better understanding of these struggles and disputes, as well as a clarification of the specific stance taken by Spinoza in this conflict, shed new light on the crisis described and diagnosed within the autonomist theories of Negri, Hardt and Virno.