publication . Article . 2017

Sleep disorders in Parkinson’s disease: approaches to treatment and prevention

M. R. Nodel; G. V. Kovrov;
Open Access Russian
  • Published: 01 Dec 2017 Journal: Nevrologiâ, Nejropsihiatriâ, Psihosomatika, volume 9, issue 4, pages 88-94 (issn: 2074-2711, eissn: 2310-1342, Copyright policy)
  • Publisher: IMA-PRESS LLC
Abstract
Nocturnal sleep disorders are one of the most important non-motor manifestations of Parkinson’s disease (PD). The clinical significance of sleep disorders in PD is determined by their frequency (up to 88%) and negative impact on quality of life in patients. The paper presents the clinical spectrum of sleep disorders in PD, current approaches to their diagnosis. It discusses the multifactorial nature of the pathophysiology of these disorders. Current views on the relationship of sleep disorders to the neurodegeneration of brain structures involved in the regulation of sleep and wakefulness, to circadian disorders and therapy are depicted. On the basis of the hete...
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free text keywords: parkinson’s disease, sleep disorders, insomnia, parasomnia, treatment for sleep disorders, lcsh:Neurology. Diseases of the nervous system, lcsh:RC346-429, Clinical significance, Circadian rhythm, Disease, Ropinirole, medicine.drug, medicine, Wakefulness, medicine.disease, medicine.symptom, business.industry, business, Parkinson's disease, Pediatrics, medicine.medical_specialty
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