Chapter 11: Genome-Wide Association Studies
Copyright policy )Chapter 11: Genome-Wide Association Studies
Genome-wide association studies (GWAS) have evolved over the last ten years into a powerful tool for investigating the genetic architecture of human disease. In this work, we review the key concepts underlying GWAS, including the architecture of common diseases, the structure of common human genetic variation, technologies for capturing genetic information, study designs, and the statistical methods used for data analysis. We also look forward to the future beyond GWAS.
- Vanderbilt University United States
- Dartmouth College United States
- Center for Human Genetics United States
QH301-705.5, Genetic Linkage, Genetic Variation, Education, Phenotype, Haplotypes, Electronic Health Records, Humans, Biology (General), Genome-Wide Association Study
QH301-705.5, Genetic Linkage, Genetic Variation, Education, Phenotype, Haplotypes, Electronic Health Records, Humans, Biology (General), Genome-Wide Association Study
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