The anti-crisis management of the economy and national security of the Russian Federation in modern conditions (pandemics, hybrid wars, competitive restrictions and anti-Russian propaganda from the West), approaches to Western sanctions as new opportunities for the development of the Russian Federation are considered. The ways of developing an innovative economy and increasing the productivity of aggregate labor as the main sources that ensure the accelerated development of the country are outlined. Attention is paid to the peculiarities of social partnership, economic and financial crises in the trends of macro - and micro-development, the role of investment as a financial source of anti-crisis management. The theoretical and practical foundations of the insolvency (bankruptcy) of enterprises and individual entrepreneurs, the methodology of the enterprise's recovery from the crisis, forecasting the results of anti-crisis management are described. Meets the requirements of the federal state educational standards of higher education of the latest generation. For undergraduate, graduate, postgraduate students and teachers of higher educational institutions of economic specialties, as well as researchers, managers and managers of firms.