Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial
Copyright policy )Efficacy and Safety of Topical Pidobenzone 4% as Adjuvant Treatment for Solar Lentigines: Result of a Randomized, Controlled, Clinical Trial
<b><i>Background/Objective:</i></b> This study aims at the evaluation of the efficacy and safety of a combination therapy based on pidobenzone 4% and fractional CO<sub>2</sub> laser or cryotherapy in the treatment of solar lentigines and the prevention of eventual posttreatment hyperchromia. <b><i>Methods:</i></b> Efficacy was clinically evaluated by grading the pigmentation level with the Skin Tone Color Scale (STCS), and by grading patients' impression through a Visual Analog Scale (VAS). <b><i>Results:</i></b> Our study shows that the associated treatment was safe and that it improves the therapeutic results on solar lentigines and prevents postiatrogenic hyperpigmentation compared with physical therapy alone. <b><i>Conclusion:</i></b> The combination of cryotherapy and pidobenzone 4% has been found to be the most useful treatment.
Adult, Aged, 80 and over, Lentigo, Male, Dose-Response Relationship, Drug, Proline, Administration, Topical, Hand Dermatoses, Middle Aged, Treatment Outcome, Cryotherapy, Lasers, Gas, Sunlight, Humans, Female, Laser Therapy, Aged, Follow-Up Studies, Skin
Adult, Aged, 80 and over, Lentigo, Male, Dose-Response Relationship, Drug, Proline, Administration, Topical, Hand Dermatoses, Middle Aged, Treatment Outcome, Cryotherapy, Lasers, Gas, Sunlight, Humans, Female, Laser Therapy, Aged, Follow-Up Studies, Skin
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