publication . Report . Article . 2020

Immediate Response to Chemotherapy in an Adult Neuroblastoma Patient Presenting with Cord Compression

Nedal Bukhari; Bachar F. Harfouch; Majid Shallal Alotaibi; Hulayel Alharbi; Omar Chamdine;
Open Access English
  • Published: 01 Jan 2020 Journal: Case Reports in Neurological Medicine (issn: 2090-6668, Copyright policy)
  • Publisher: Hindawi
We report a case of a 31-year-old female patient with high-risk neuroblastoma (NBL) who presented with a history of static back pain and bilateral lower limb weakness for almost a month. Her primary tumor was located in the right paraspinal region, causing spinal cord compression (SCC). Chemotherapy was administered with an immediate clinical improvement noted after 24 hours of starting treatment. We herein report the efficacy of chemotherapy in an adult neuroblastoma (aNBL) patient presenting with spinal cord compression.
Persistent Identifiers
free text keywords: Article Subject, Case Report, Neurology. Diseases of the nervous system, RC346-429, Surgery, medicine.medical_specialty, medicine, Spinal cord compression, medicine.disease, Female patient, business.industry, business, Chemotherapy, medicine.medical_treatment, Cord, Neuroblastoma, Lower limb weakness, Primary tumor, Back pain, medicine.symptom
Related Organizations

Davis, S., Rogers, M. A. M., Pendergrass, T. W.. The incidence and epidemiologic characteristics of neuroblastoma in the United States. American Journal of Epidemiology . 1987; 126 (6): 1063-1074 [OpenAIRE] [PubMed] [] [DOI]

Castleberry, R. P.. Biology and treatment of neuroblastoma. Pediatric Clinics of North America . 1997; 44 (4): 919-937 [OpenAIRE] [PubMed] [] [DOI]

Francks, L. M., Bollen, A., Seeger, R. C., Tram, D. O., Matthay, K. K.. Neuroblastoma in adults and adolescents: an indolent course with poor survival. Cancer . 1997; 79 (10): 2028-2035 [OpenAIRE] [PubMed] [DOI]

Conter, H. J., Gopalakrishnan, V., Ravi, V., Ater, J. L., Patel, S., Araujo, D. M.. Adult versus pediatric neuroblastoma: the M.D. Anderson cancer center experience. Sarcoma . 2014; 2014: 6 [OpenAIRE] [] [] [DOI]

Sait, S., Modak, S.. Anti-GD2 immunotherapy for neuroblastoma. Expert Review of Anticancer Therapy . 2017; 17 (10): 889-904 [OpenAIRE] [PubMed] [] [DOI]

Pinto, N. R., Applebaum, M. A., Volchenboum, S. L.. Advances in risk classification and treatment strategies for neuroblastoma. Journal of Clinical Oncology . 2015; 33 (27): 3008-3017 [OpenAIRE] [PubMed] [] [DOI]

Bernardi, B. D., Balwierz, W., Bejent, J.. Epidural compression in neuroblastoma: diagnostic and therapeutic aspects. Cancer Letters . 2005; 228 (1-2): 283-299 [OpenAIRE] [PubMed] [] [DOI]

Poretti, A., Grotzer, M. A.. Neuroblastoma with spinal cord compression: is there an emergency treatment of choice?. Developmental Medicine & Child Neurology . 2012; 54 (4): 297-298 [OpenAIRE] [PubMed] [] [DOI]

Fawzy, M., El-Beltagy, M., Shafei, M. E.. Intraspinal neuroblastoma: treatment options and neurological outcome of spinal cord compression. Oncology Letters . 2015; 9 (2): 907-911 [OpenAIRE] [PubMed] [] [DOI]

Plantaz, D., Rubie, H., Michon, J.. The treatment of neuroblastoma with intraspinal extension with chemotherapy followed by surgical removal of residual disease: a prospective study of 42 patients—results of the NBL 90 study of the French Society of Pediatric Oncology. Cancer . 1996; 78 (2): 311-319 [OpenAIRE] [PubMed] [DOI]

Urios, J. I., Garceran, L. R., Rosell, T. V.. Neuroblastoma in an adult causing spinal cord compression: report of a case and review of the literature. Spinal Cord . 1989; 27 (5): 394-401 [OpenAIRE] [] [DOI]

Jost, G., Frank, S., Fischer, N., Taub, E., Mariani, L.. An epidural neuroblastoma causing spinal cord compression in a 67-year-old woman. Rare Tumors . 2010; 2 (2): 74-77 [OpenAIRE] [] [DOI]

Simon, T., Häberle, B., Hero, B., von Schweinitz, D., Berthold, F.. Role of surgery in the treatment of patients with stage 4 neuroblastoma age 18 months or older at diagnosis. Journal of Clinical Oncology . 2013; 31 (6): 752-758 [PubMed] [] [DOI]

Patrick, L., Johnson, D. B., Thompson, M. A., Keedy, V. L., Frangoul, H. A., Snyder, K. M.. Adult neuroblastoma complicated by increased intracranial pressure: a case report and review of the literature. Case Reports in Oncological Medicine . 2014; 2014: 5 [OpenAIRE] [] [DOI]

Any information missing or wrong?Report an Issue