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handle: 11104/0351234
A new spontaneous mutation, abnormal hair appearance in the rat, has been identified as a nonfunctional tuftelin 1 ( Tuft1) gene. The pleiotropic effects of this mutation regulate glucose and lipid metabolism. Analysis of the liver proteome revealed possible molecular mechanisms for the metabolic effects of the Tuft1 gene.
rat, spontaneous nonsense mutation, Tuft1, tuftelin 1 gene, hepatic proteome, lipid and glucose metabolism
rat, spontaneous nonsense mutation, Tuft1, tuftelin 1 gene, hepatic proteome, lipid and glucose metabolism
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