The rate of disappearance of ethanol from the entire body is usually expressed as mg/kg per hr, which has been designated B sub 60. For humans the average B sub 60 is about 100. It is fairly constant for a given person but varies among individuals, with extremes of about 50 and 200. Essentially the same information may be obtained from the slope of the curve for blood ethanol concentration, which like B sub 60, is a straight line. This is the Widmark Beta factor. It is now expressed as mg percent per hr, and designated as Beta sub 60. For humans the average Beta sub 60 is about 15, with extremes of 10 to 20. This paper considers certain chemicals (drugs) which offer promise of altering B sub 60 and Beta sub 60, and two other procedures of perhaps dubious efficacy. Both live animal and human subject tests were performed.