Introduction (G P Rangaiah) Multi-Objective Optimization Applications in Chemical Engineering (Masuduzzaman & G P Rangaiah) Techniques: Multi-Objective Evolutionary Algorithms: A Review of the State of the Art and Some of Their Applications in Chemical Engineering (A L Jaimes & C A Coello Coello) The Jumping Gene Adaptations of Multi-Objective Genetic Algorithm and Simulated Annealing (M Ramteke & S K Gupta) Multi-Objective Optimization Using Surrogate-Assisted Evolutionary Algorithm (T Ray) Why Use Interactive Multi-Objective Optimization in Chemical Process Design? (K Miettinen & J Hakanen) Net Flow and Rough Set: Two Methods for Ranking the Pareto Domain (J Thibault) Applications: Multi-Objective Optimization of Gas-Phase Refrigeration Systems for LNG (N Shah et al.) A Multi-Objective Evolutionary Algorithm for Practical Residue Catalytic Cracking Feed Optimization (K C Tan et al.) Optimal Design of Chemical Processes for Multiple Economic and Environmental Objectives (E S Q Lee et al.) Multi-Objective Emergency Response Optimization around Chemical Plants (P S Georgiadou et al.) Array Informatics Using Multi-Objective Genetic Algorithms: From Gene Expressions to Gene Networks (S Garg) Multi-Objective Optimization of a Multi-Product Microbial Cell Factory for Multiple Objectives - A Paradigm for Metabolic Pathway Recipe (F C Lee et al.).