A consequence of being a specialty with several organs is that gastroenterologists see patients who report a range of symptoms. And while we may subspecialise in one area or another, a lot of what comes through our door is a reflection of the high prevalence of gastrointestinal and hepatological symptoms, test abnormalities and diseases. This edition of Frontline Gastroenterology has a diverse range of papers which address the catholic nature of our specialty. Recent years have seen a major increase in the number of liver enzyme bloods (liver function tests, LFTs) being undertaken, possibly related to the increasing prevalence of non-alcoholic fatty liver disease requiring early identification and intervention, as well as an increasing ability to treat diagnosed liver disease, such as viral hepatitis. As many as 1 in 5 of these blood tests are abnormal, potentially needing further diagnostic work-up. Miller and colleagues1 report an initiative to introduce a streamlined, efficient direct approach to resolve this …