Ed R A Eeles, B A J Ponder, D F Easton, A Horwich Chapman and Hall, £60, pp 432 ISBN 0412 565 803 Referrals for advice about genetic predisposition to cancer have increased exponentially in almost all regional genetics centres across Britain, reflecting increasing public awareness of the association between a family history of cancer and a personal increase in risk. In almost any specialty, but particularly those concerned closely with cancer, doctors need at least a working knowledge of how genes can predispose to cancer, when it might be appropriate to refer patients to clinical genetics services for further investigation or advice, what …