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Antimicrobial Agents and Chemotherapy
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Antimicrobial Agents and Chemotherapy
Article . 2015 . Peer-reviewed
License: ASM Journals Non-Commercial TDM
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Antimicrobial Agents and Chemotherapy
Article . 2015
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https://dx.doi.org/10.1128/aac...
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Synergistic Activity of Chloroquine with Fluconazole against Fluconazole-Resistant Isolates of Candida Species

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2015 English Publisher:American Society for MicrobiologyJournal:Antimicrobial Agents and Chemotherapy, volume 59, pages 1,365-1,369 (issn: 0066-4804, eissn: 1098-6596, Copyright policy )
Authors: Yali, Li; Zhe, Wan; Wei, Liu; Ruoyu, Li;

doi: 10.1128/aac.04417-14

pmid: 25512426

pmc: PMC4335839

Synergistic Activity of Chloroquine with Fluconazole against Fluconazole-Resistant Isolates of Candida Species

Abstract

ABSTRACT The in vitro activity of chloroquine and the interactions of chloroquine combined with fluconazole against 37 Candida isolates were tested using the broth microdilution, disk diffusion, and Etest susceptibility tests. Synergistic effect was detected with 6 of 9 fluconazole-resistant Candida albicans isolates, with Candida krusei ATCC 6258, and with all 12 fluconazole-resistant Candida tropicalis isolates.

Related Organizations
Keywords

Antifungal Agents, Drug Resistance, Fungal, Chloroquine, Drug Synergism, Microbial Sensitivity Tests, Fluconazole, Candida

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 20
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
20
Top 10%
Top 10%
Top 10%
bronze
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